CDK9

GENE INFORMATION

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Gene name

CDK9 (HGNC Symbol)

Synonyms

C-2k, CDC2L4, PITALRE, TAK

Description

cyclin-dependent kinase 9 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

q34.11

Chromosome location (bp)

130547958 - 130553066

Ensembl

ENSG00000136807 (version 73.37)

Entrez gene

1025

UniProt

P50750 (UniProt - Evidence at protein level)

neXtProt

NX_P50750

Antibodypedia

CDK9 antibodies
 

PROTEIN VIEW

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CDK9-001
 
CDK9-005
 
CDK9-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDK9-001 ENSP00000362361
ENST00000373264
P50750
Show all »
Show » Show » 372 42.8 No 0
CDK9-005 ENSP00000395872
ENST00000421939
P50750
Show all »
Show » Show » 194 19.5 No 0
CDK9-201 ENSP00000362362
ENST00000373265
P50750
Show all »
Show » Show » 489 53.4 No 0