Fields »

SUBCELLULAR LOCATION

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Main location(s)

Nucleus but not nucleoli

Additional location(s)

Cytoplasm, Cytoskeleton (Intermediate filaments) 

Staining summary

Mainly localized to the nucleus. In addition localized to cytoplasm and/or intermediate filaments.

Reliability (APE)

Low

Antibodies in assay

HPA013697, CAB022709
 

Antibody HPA013697

 

Antibody CAB022709

 

         Cell line A-431

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Location(s)

Nucleus but not nucleoli, Cytoplasm, Cytoskeleton (Intermediate filaments) Nucleus but not nucleoli, Cytoplasm 

Staining characteristics

Granular Speckle 

Staining intensity

Weak Strong 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

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Location(s)

  Nucleus but not nucleoli, Cytoplasm 

Staining characteristics

  Speckle 

Staining intensity

  Strong 

Validation

  
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

   

         Cell line U-251 MG

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Location(s)

  Nucleus but not nucleoli, Cytoplasm 

Staining characteristics

  Speckle 

Staining intensity

  Strong 

Validation

  
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

   

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in nucleus but not nucleoli, cytoplasm & cytoskeleton (intermediate filaments).
 

Immunofluorescent staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm.
 

Summary

Staining of nucleus, cytoplasm and cytoskeleton (intermediate filaments) in A-431.   Staining of nucleus and cytoplasm in all three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cytoplasm
Intermediate filaments
Nucleus but not nucleoli