PSMB7

GENE INFORMATION

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Gene name

PSMB7 (HGNC Symbol)

Synonyms

Z

Description

proteasome (prosome, macropain) subunit, beta type, 7 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]

Chromosome

9 (Chromosome progress)

Cytoband

q33.3

Chromosome location (bp)

127115745 - 127177723

Ensembl

ENSG00000136930 (version 73.37)

Entrez gene

5695

UniProt

Q99436 (UniProt - Evidence at protein level)

neXtProt

NX_Q99436

Antibodypedia

PSMB7 antibodies
 

PROTEIN VIEW

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PSMB7-001
 
PSMB7-003
 
PSMB7-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMB7-001 ENSP00000259457
ENST00000259457
Q99436
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Show » Show » 277 30 No 0
PSMB7-003 ENSP00000393157
ENST00000441097
Q5TBG5
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Show » 210 22.8 No 0
PSMB7-201 ENSP00000440247
ENST00000536392
B4E0P1
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Show » 142 15.3 No 0