Fields »

SUBCELLULAR LOCATION

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Main location(s)

Plasma membrane

Additional location(s)

Nucleus but not nucleoli 

Staining summary

Mainly localized to the plasma membrane but also to the nucleus.

Reliability (APE)

Low

Antibodies in assay

HPA031602, HPA031603, HPA031604
 

Antibody HPA031602

 

Antibody HPA031603

 

Antibody HPA031604

 

         Cell line A-431

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Location(s)

  Nucleus but not nucleoli, Plasma membrane  

Staining characteristics

    

Staining intensity

  Weak Negative 

Validation

  
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 
No staining.
 

Comment

    

         Cell line U-2 OS

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Location(s)

     

Staining characteristics

     

Staining intensity

    Negative 

Validation

    
No staining.
 

Comment

     

         Cell line U-251 MG

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Location(s)

    

Staining characteristics

    

Staining intensity

Negative   Negative 

Validation

No staining.
   
No staining.
 

Comment

    

         Antibody summary


Immunofluorescent staining of human cell line U-251 MG shows no positivity.
 

Immunofluorescent staining of human cell line A-431 shows positivity in nucleus but not nucleoli & plasma membrane.
 

Immunofluorescent staining of human cell line U-2 OS shows no positivity.
 

Summary

No staining was observed in the three cell lines.   Staining of nucleus and plasma membrane in A-431.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is supported by literature.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Nucleus but not nucleoli
Plasma membrane