MRPL15

GENE INFORMATION

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Gene name

MRPL15 (HGNC Symbol)

Synonyms

HSPC145, L15mt, MRP-L15, MRP-L7, RPML7

Description

mitochondrial ribosomal protein L15 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008]

Chromosome

8 (Chromosome progress)

Cytoband

q11.23

Chromosome location (bp)

55047770 - 55060461

Ensembl

ENSG00000137547 (version 73.37)

Entrez gene

29088

UniProt

Q9P015 (UniProt - Evidence at protein level)

neXtProt

NX_Q9P015

Antibodypedia

MRPL15 antibodies
 

PROTEIN VIEW

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MRPL15-001
 
MRPL15-002
 
MRPL15-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL15-001 ENSP00000260102
ENST00000260102
Q9P015
Show all »
Show » Show » 296 33.4 No 0
MRPL15-002 ENSP00000429252
ENST00000522521
E5RIZ4
Show all »
Show » 93 10.8 No 0
MRPL15-003 ENSP00000428581
ENST00000519831
E5RHF4
Show all »
Show » 198 21.9 No 0