NEK1

GENE INFORMATION

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Gene name

NEK1 (HGNC Symbol)

Synonyms

KIAA1901, NY-REN-55

Description

NIMA-related kinase 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Chromosome

4 (Chromosome progress)

Cytoband

q33

Chromosome location (bp)

170314426 - 170533780

Ensembl

ENSG00000137601 (version 73.37)

Entrez gene

4750

UniProt

Q96PY6 (UniProt - Evidence at protein level)

neXtProt

NX_Q96PY6

Antibodypedia

NEK1 antibodies
 

PROTEIN VIEW

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NEK1-001
 
NEK1-002
 
NEK1-003
 
NEK1-004
 
NEK1-005
 
NEK1-006
 
NEK1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NEK1-001 ENSP00000408020
ENST00000439128
Q96PY6
Show all »
Show » Show » 1258 142.8 No 0
NEK1-002 ENSP00000427653
ENST00000510533
Q96PY6
Show all »
Show » Show » 1214 138.1 No 0
NEK1-003 ENSP00000423332
ENST00000511633
Q96PY6
Show all »
Show » Show » 1242 141.1 No 0
NEK1-004 ENSP00000424757
ENST00000507142
Q96PY6
Show all »
Show » Show » 1286 145.8 No 0
NEK1-005 ENSP00000424938
ENST00000512193
Q96PY6
Show all »
Show » Show » 1189 135.3 No 0
NEK1-006 ENSP00000424152
ENST00000510108
D6RBG5
Show all »
Show » 45 5.1 No 0
NEK1-008 ENSP00000421525
ENST00000505119
Show » 123 13.9 No 0