PAK6

GENE INFORMATION

? »

Gene name

PAK6 (HGNC Symbol)

Synonyms

PAK5

Description

p21 protein (Cdc42/Rac)-activated kinase 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Chromosome

15 (Chromosome progress)

Cytoband

q15.1

Chromosome location (bp)

40509629 - 40569688

Ensembl

ENSG00000137843 (version 73.37)

Entrez gene

56924

UniProt

Q9NQU5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQU5

Antibodypedia

PAK6 antibodies
 

PROTEIN VIEW

? »
 
 
 « 
 
PAK6-001
 
PAK6-002
 
PAK6-003
 
PAK6-004
 
PAK6-005
 
PAK6-006
 
PAK6-007
 
PAK6-008
 
PAK6-009
 
PAK6-010
 
PAK6-011
 
PAK6-012
 
PAK6-013
 
PAK6-014
 
PAK6-201
 
PAK6-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PAK6-001 ENSP00000260404
ENST00000260404
Q9NQU5
Show all »
Show » Show » 681 74.9 No 0
PAK6-002 ENSP00000409465
ENST00000455577
G5E9R2
Show all »
Show » 636 69.8 No 0
PAK6-003 ENSP00000453858
ENST00000560346
Q9NQU5
Show all »
Show » Show » 681 74.9 No 0
PAK6-004 ENSP00000439597
ENST00000542403
Q9NQU5
Show all »
Show » Show » 681 74.9 No 0
PAK6-005 ENSP00000453520
ENST00000561230
H0YM99
Show all »
105 12 No 0
PAK6-006 ENSP00000453407
ENST00000558055
H0YLZ9
Show all »
122 13.9 No 0
PAK6-007 ENSP00000452737
ENST00000558878
H0YKB6
Show all »
58 6.8 No 0
PAK6-008 ENSP00000452647
ENST00000558183
H0YK38
Show all »
74 8.6 No 0
PAK6-009 ENSP00000453005
ENST00000560806
H0YL02
Show all »
20 2.3 No 0
PAK6-010 ENSP00000452708
ENST00000559617
H0YK91
Show all »
112 12.8 No 0
PAK6-011 ENSP00000453721
ENST00000558106
H0YMS4
Show all »
123 14 No 0
PAK6-012 ENSP00000453057
ENST00000560684
H0YL47
Show all »
71 8.3 No 0
PAK6-013 ENSP00000452686
ENST00000559139
H0YK74
Show all »
109 12.5 No 0
PAK6-014 ENSP00000453021
ENST00000560669
H0YL16
Show all »
284 30.7 No 0
PAK6-201 ENSP00000406873
ENST00000441369
Q9NQU5
Show all »
Show » Show » 681 74.9 No 0
PAK6-202 ENSP00000401153
ENST00000453867
Q9NQU5
Show all »
Show » Show » 681 74.9 No 0