FNBP1L

GENERAL INFORMATION

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Gene name

FNBP1L

Gene description

Formin binding protein 1-like

Protein class

Cytoskeleton related proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA065273
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

FNBP1L (HGNC Symbol)

Synonyms

C1orf39, FLJ20275, TOCA1

Description

Formin binding protein 1-like (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p22.1

Chromosome location (bp)

93448131 - 93554661

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137942 (version 78.38)

Entrez gene

54874

UniProt

Q5T0N5 (UniProt - Evidence at protein level)

neXtProt

NX_Q5T0N5

Antibodypedia

FNBP1L antibodies


PROTEIN BROWSER

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ENST00000260506
 
ENST00000271234
 
ENST00000370253
 
ENST00000424449
 
ENST00000604705
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FNBP1L-001 ENSP00000359275
ENST00000370253
Q5T0N5
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Show » Show » 547 63.6 No 0
FNBP1L-002 ENSP00000473921
ENST00000604705
S4R347
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Show » Show » 609 70.5 No 0
FNBP1L-003 ENSP00000397451
ENST00000424449
B4DSI7
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Show » Show » 451 51.2 No 0
FNBP1L-201 ENSP00000260506
ENST00000260506
Q5T0N5
Show all »
Show » Show » 551 64 No 0
FNBP1L-202 ENSP00000271234
ENST00000271234
Q5T0N5
Show all »
Show » Show » 605 70.1 No 0