CYP2C9

GENE INFORMATION

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Gene name

CYP2C9 (HGNC Symbol)

Synonyms

CYP2C10, P450IIC9

Description

cytochrome P450, family 2, subfamily C, polypeptide 9 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q23.33

Chromosome location (bp)

96698415 - 96749147

Ensembl

ENSG00000138109 (version 73.37)

Entrez gene

1559

UniProt

P11712 (UniProt - Evidence at protein level)

neXtProt

NX_P11712

Antibodypedia

CYP2C9 antibodies
 

PROTEIN VIEW

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CYP2C9-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP2C9-001 ENSP00000260682
ENST00000260682
P11712
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