SSB

GENE INFORMATION

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Gene name

SSB (HGNC Symbol)

Synonyms

La, LARP3

Description

Sjogren syndrome antigen B (autoantigen La) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. [provided by RefSeq, Nov 2011]

Chromosome

2 (Chromosome progress)

Cytoband

q31.1

Chromosome location (bp)

170648443 - 170668574

Ensembl

ENSG00000138385 (version 73.37)

Entrez gene

6741

UniProt

P05455 (UniProt - Evidence at protein level)

neXtProt

NX_P05455

Antibodypedia

SSB antibodies
 

PROTEIN VIEW

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SSB-001
 
SSB-003
 
SSB-004
 
SSB-005
 
SSB-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SSB-001 ENSP00000260956
ENST00000260956
P05455
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Show » 408 46.8 No 0
SSB-003 ENSP00000386636
ENST00000409333
P05455
Show all »
Show » 408 46.8 No 0
SSB-004 ENSP00000397029
ENST00000422006
E7ERC4
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Show » 184 21.4 No 0
SSB-005 ENSP00000396890
ENST00000417292
E9PGX9
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Show » 120 13.9 No 0
SSB-006 ENSP00000395758
ENST00000413002
E9PFL9
Show all »
Show » 134 15.5 No 0