The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Normal tissues showed weak to moderate cytoplasmic staining with occasional nuclear positivity in several tissues. The adrenal, gall bladder, small intestine, prostate, epididymis, seminal vesicles, chondrocytes and Leydig cells displayed strong positivity. Bile duct cells, islets of Langerhans, parathyroid, cells in glomeruli, placenta, smooth muscle and the CNS tissues were negative.
Most normal tissues displayed weak to moderate cytoplasmic and nuclear positivity. Leydig cells and chondrocytes were strongly stained. Squamous epithelial cells, cells of CNS, lymphoid and muscle tissues were negative.
Normal tissues displayed weak to moderate cytoplasmic staining with additional nuclear positivity in several tissues. Adrenocortical cells, gall bladder, chondrocytes, urinary bladder, male genital tract and glandular cells of uterus were strongly stained. Lymphoid tissue and bile duct cells were negative.
Male reproductive organs, urothelium, adrenal glands and endometrium showed moderate nuclear and/or cytoplasmic positivity. Other normal tissues were in general negative.