GLCE

GENE INFORMATION

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Gene name

GLCE (HGNC Symbol)

Synonyms

HSEPI, KIAA0836

Description

glucuronic acid epimerase (HGNC Symbol)

Entrez gene summary

Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM, Jun 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q23

Chromosome location (bp)

69452923 - 69564556

Ensembl

ENSG00000138604 (version 73.37)

Entrez gene

26035

UniProt

O94923 (UniProt - Evidence at protein level)

neXtProt

NX_O94923

Antibodypedia

GLCE antibodies
 

PROTEIN VIEW

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GLCE-001
 
GLCE-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GLCE-001 ENSP00000454092
ENST00000559420
H0YNP1
Show all »
Show » 553 62.9 No 0
GLCE-201 ENSP00000261858
ENST00000261858
O94923
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Show » Show » 617 70.1 Yes 0