PPCDC

GENE INFORMATION

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Gene name

PPCDC (HGNC Symbol)

Synonyms

FLJ14585, MDS018

Description

Phosphopantothenoylcysteine decarboxylase (HGNC Symbol)

Entrez gene summary

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]

Chromosome

15

Cytoband

q24.2

Chromosome location (bp)

75315896 - 75409803

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000138621 (version 75.37)

Entrez gene

60490

UniProt

Q96CD2 (UniProt - Evidence at protein level)

neXtProt

NX_Q96CD2

Antibodypedia

PPCDC antibodies
 

PROTEIN VIEW

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PPCDC-001
 
PPCDC-002
 
PPCDC-003
 
PPCDC-005
 
PPCDC-006
 
PPCDC-007
 
PPCDC-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPCDC-001 ENSP00000343190
ENST00000342932
Q96CD2
Show all »
Show » Show » 204 22.4 No 0
PPCDC-002 ENSP00000457490
ENST00000563393
H3BU63
Show all »
Show » Show » 81 9 No 0
PPCDC-003 ENSP00000455499
ENST00000569562
H3BPW5
Show all »
Show » Show » 64 7 No 0
PPCDC-005 ENSP00000456665
ENST00000564923
H3BSE3
Show all »
Show » Show » 129 14 No 0
PPCDC-006 ENSP00000456353
ENST00000567336
H3BRQ0
Show all »
Show » Show » 172 18.7 No 0
PPCDC-007 ENSP00000455691
ENST00000568649
H3BQB0
Show all »
Show » Show » 161 17.6 No 0
PPCDC-008 ENSP00000457446
ENST00000562095
H3BU34
Show all »
Show » Show » 62 6.6 No 0