HCN4

GENE INFORMATION

? »

Gene name

HCN4

Synonyms

Description

hyperpolarization activated cyclic nucleotide-gated potassium channel 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q24.1

Chromosome location (bp)

73612200 - 73661605

Ensembl

ENSG00000138622 (version 73.37)

Entrez gene

10021

UniProt

Q9Y3Q4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y3Q4

Antibodypedia

HCN4 antibodies
 

PROTEIN VIEW

? »
 
 
 
HCN4-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HCN4-001 ENSP00000261917
ENST00000261917
Q9Y3Q4
Show all »
Show » Show » 1203 129 No 5