SEMA7A

GENE INFORMATION

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Gene name

SEMA7A (HGNC Symbol)

Synonyms

CD108, H-Sema-L, SEMAL

Description

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene binds to cell surfaces through a glycosylphosphatidylinositol (GPI) linkage. The encoded glycoprotein is found on activated lymphocytes and erythrocytes. This protein may be involved in immunomodulatory and neuronal processes. Defects in this gene can result in loss of bone mineral density (BMD). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

Chromosome

15 (Chromosome progress)

Cytoband

q24.1

Chromosome location (bp)

74701630 - 74726808

Ensembl

ENSG00000138623 (version 73.37)

Entrez gene

8482

UniProt

O75326 (UniProt - Evidence at protein level)

neXtProt

NX_O75326

Antibodypedia

SEMA7A antibodies
 

PROTEIN VIEW

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SEMA7A-001
 
SEMA7A-002
 
SEMA7A-005
 
SEMA7A-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SEMA7A-001 ENSP00000261918
ENST00000261918
O75326
Show all »
Show » Show » 666 74.8 Yes 1
SEMA7A-002 ENSP00000438966
ENST00000543145
O75326
Show all »
Show » Show » 652 73.4 Yes 1
SEMA7A-005 ENSP00000454365
ENST00000567345
H3BMF9
Show all »
Show » 80 9.6 No 0
SEMA7A-201 ENSP00000441493
ENST00000542748
F5GYX3
Show all »
Show » Show » 501 57.1 No 1