HERC6

GENE INFORMATION

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Gene name

HERC6 (HGNC Symbol)

Synonyms

FLJ20637

Description

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 (HGNC Symbol)

Entrez gene summary

HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

89299891 - 89364263

Ensembl

ENSG00000138642 (version 73.37)

Entrez gene

55008

UniProt

Q8IVU3 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8IVU3

Antibodypedia

HERC6 antibodies
 

PROTEIN VIEW

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HERC6-001
 
HERC6-002
 
HERC6-003
 
HERC6-006
 
HERC6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HERC6-001 ENSP00000264346
ENST00000264346
Q8IVU3
Show all »
Show » Show » 1022 115.1 No 1
HERC6-002 ENSP00000425504
ENST00000504905
D6RCT4
Show all »
73 7.9 No 0
HERC6-003 ENSP00000369617
ENST00000380265
Q8IVU3
Show all »
Show » Show » 986 111.1 No 1
HERC6-006 ENSP00000425060
ENST00000502870
186 19.5 No 0
HERC6-201 ENSP00000273960
ENST00000273960
Q8IVU3
Show all »
Show » 306 32.7 No 0