FGF2

GENE INFORMATION

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Gene name

FGF2 (HGNC Symbol)

Synonyms

FGFB

Description

fibroblast growth factor 2 (basic) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q27

Chromosome location (bp)

123747863 - 123819391

Ensembl

ENSG00000138685 (version 73.37)

Entrez gene

2247

UniProt

P09038 (UniProt - Evidence at protein level)

neXtProt

NX_P09038

Antibodypedia

FGF2 antibodies
 

PROTEIN VIEW

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FGF2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF2-001 ENSP00000264498
ENST00000264498
P09038
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