CDKL2

GENERAL INFORMATION

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Gene name

CDKL2

Gene description

Cyclin-dependent kinase-like 2 (CDC2-related kinase)

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (testis)
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in selected tissues. RNA-based expert annotation could not be performed.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA040672
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Lung

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

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Gene name

CDKL2 (HGNC Symbol)

Synonyms

KKIAMRE, P56

Description

Cyclin-dependent kinase-like 2 (CDC2-related kinase) (HGNC Symbol)

Entrez gene summary

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

q21.1

Chromosome location (bp)

75578005 - 75630716

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000138769 (version 78.38)

Entrez gene

8999

UniProt

Q92772 (UniProt - Evidence at protein level)

neXtProt

NX_Q92772

Antibodypedia

CDKL2 antibodies


PROTEIN BROWSER

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ENST00000307465
 
ENST00000429927
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDKL2-001 ENSP00000412365
ENST00000429927
Q92772
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Show » Show » 493 56 No 0
CDKL2-002 ENSP00000306340
ENST00000307465
J3KNE8
Show all »
Show » Show » 570 64.8 No 0