PRICKLE1

GENE INFORMATION

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Gene name

PRICKLE1 (HGNC Symbol)

Synonyms

EPM1B, FLJ31937

Description

prickle homolog 1 (Drosophila) (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]

Chromosome

12 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

42852140 - 42984157

Ensembl

ENSG00000139174 (version 73.37)

Entrez gene

144165

UniProt

Q96MT3 (UniProt - Evidence at protein level)

neXtProt

NX_Q96MT3

Antibodypedia

PRICKLE1 antibodies
 

PROTEIN VIEW

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PRICKLE1-001
 
PRICKLE1-002
 
PRICKLE1-003
 
PRICKLE1-004
 
PRICKLE1-005
 
PRICKLE1-006
 
PRICKLE1-007
 
PRICKLE1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRICKLE1-001 ENSP00000345064
ENST00000345127
Q96MT3
Show all »
Show » Show » 831 94.3 No 0
PRICKLE1-002 ENSP00000446699
ENST00000547113
F8W1Q8
Show all »
Show » 110 12.6 No 0
PRICKLE1-003 ENSP00000448359
ENST00000548696
Q96MT3
Show all »
Show » Show » 831 94.3 No 0
PRICKLE1-004 ENSP00000449819
ENST00000552240
Q96MT3
Show all »
Show » Show » 831 94.3 No 0
PRICKLE1-005 ENSP00000398947
ENST00000445766
Q96MT3
Show all »
Show » Show » 831 94.3 No 0
PRICKLE1-006 ENSP00000447870
ENST00000552108
F8VUG8
Show all »
Show » 159 17.8 No 0
PRICKLE1-007 ENSP00000446970
ENST00000551050
F8W1J1
Show all »
Show » 119 13.7 No 0
PRICKLE1-201 ENSP00000401060
ENST00000455697
Q96MT3
Show all »
Show » Show » 831 94.3 No 0