LUM

GENE INFORMATION

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Gene name

LUM (HGNC Symbol)

Synonyms

LDC, SLRR2D

Description

lumican (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]

Chromosome

12 (Chromosome progress)

Cytoband

q21.33

Chromosome location (bp)

91496406 - 91505608

Ensembl

ENSG00000139329 (version 73.37)

Entrez gene

4060

UniProt

P51884 (UniProt - Evidence at protein level)

neXtProt

NX_P51884

Antibodypedia

LUM antibodies
 

PROTEIN VIEW

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LUM-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LUM-001 ENSP00000266718
ENST00000266718
P51884
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