CELA1

GENE INFORMATION

? »

Gene name

CELA1 (HGNC Symbol)

Synonyms

ELA1

Description

chymotrypsin-like elastase family, member 1 (HGNC Symbol)

Entrez gene summary

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]

Chromosome

12 (Chromosome progress)

Cytoband

q13.13

Chromosome location (bp)

51722227 - 51740463

Ensembl

ENSG00000139610 (version 73.37)

Entrez gene

1990

UniProt

Q9UNI1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNI1

Antibodypedia

CELA1 antibodies
 

PROTEIN VIEW

? »
 
 
 
CELA1-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CELA1-001 ENSP00000293636
ENST00000293636
Q9UNI1
Show all »
Show » Show » 258 27.8 No 0