SMARCC2

GENERAL INFORMATION

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Gene name

SMARCC2

Gene description

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA021213 , CAB004321
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SMARCC2 (HGNC Symbol)

Synonyms

BAF170, CRACC2, Rsc8

Description

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.2

Chromosome location (bp)

56162983 - 56189567

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000139613 (version 78.38)

Entrez gene

6601

UniProt

Q8TAQ2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TAQ2

Antibodypedia

SMARCC2 antibodies


PROTEIN BROWSER

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ENST00000267064
 
ENST00000347471
 
ENST00000394023
 
ENST00000550164
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMARCC2-001 ENSP00000267064
ENST00000267064
Q8TAQ2
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Show » Show » 1214 132.9 No 0
SMARCC2-002 ENSP00000302919
ENST00000347471
Q8TAQ2
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Show » Show » 1130 124.8 No 0
SMARCC2-003 ENSP00000377591
ENST00000394023
Q8TAQ2
Show all »
Show » Show » 1152 126.9 No 0
SMARCC2-006 ENSP00000449396
ENST00000550164
F8VXC8
Show all »
Show » Show » 1245 136.2 No 0