DENR

GENE INFORMATION

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Gene name

DENR (HGNC Symbol)

Synonyms

DRP, DRP1, SMAP-3

Description

density-regulated protein (HGNC Symbol)

Entrez gene summary

This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]

Chromosome

12 (Chromosome progress)

Cytoband

q24.31

Chromosome location (bp)

123237321 - 123255611

Ensembl

ENSG00000139726 (version 73.37)

Entrez gene

8562

UniProt

O43583 (UniProt - Evidence at protein level)

neXtProt

NX_O43583

Antibodypedia

DENR antibodies
 

PROTEIN VIEW

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DENR-001
 
DENR-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DENR-001 ENSP00000280557
ENST00000280557
O43583
Show all »
Show » 198 22.1 No 0
DENR-002 ENSP00000413661
ENST00000455982
F8VVL1
Show all »
Show » 160 17.8 No 0