SLC12A6

GENE INFORMATION

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Gene name

SLC12A6 (HGNC Symbol)

Synonyms

ACCPN, KCC3

Description

solute carrier family 12 (potassium/chloride transporters), member 6 (HGNC Symbol)

Entrez gene summary

This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q14

Chromosome location (bp)

34525460 - 34630261

Ensembl

ENSG00000140199 (version 73.37)

Entrez gene

9990

UniProt

Q9UHW9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHW9

Antibodypedia

SLC12A6 antibodies
 

PROTEIN VIEW

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 « 
 
SLC12A6-001
 
SLC12A6-002
 
SLC12A6-003
 
SLC12A6-004
 
SLC12A6-005
 
SLC12A6-006
 
SLC12A6-007
 
SLC12A6-008
 
SLC12A6-009
 
SLC12A6-010
 
SLC12A6-011
 
SLC12A6-012
 
SLC12A6-013
 
SLC12A6-017
 
SLC12A6-018
 
SLC12A6-020
 
SLC12A6-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC12A6-001 ENSP00000290209
ENST00000290209
Q9UHW9
Show all »
Show » Show » 1099 122.1 No >9
SLC12A6-002 ENSP00000380819
ENST00000397707
Q9UHW9
Show all »
Show » Show » 1135 126 No >9
SLC12A6-003 ENSP00000346112
ENST00000354181
Q9UHW9
Show all »
Show » Show » 1150 127.6 No >9
SLC12A6-004 ENSP00000452776
ENST00000558589
Q9UHW9
Show all »
Show » Show » 1141 126.6 No >9
SLC12A6-005 ENSP00000452904
ENST00000559523
H0YKQ8
Show all »
Show » Show » 942 103.8 No >9
SLC12A6-006 ENSP00000387725
ENST00000458406
Q9UHW9
Show all »
Show » Show » 1091 121.1 No >9
SLC12A6-007 ENSP00000453702
ENST00000559664
H0YMQ9
Show all »
Show » Show » 906 99.3 No >9
SLC12A6-008 ENSP00000380814
ENST00000397702
Q9UHW9
Show all »
Show » Show » 1091 121.1 No >9
SLC12A6-009 ENSP00000453473
ENST00000558667
Q9UHW9
Show all »
Show » Show » 1150 127.6 No >9
SLC12A6-010 ENSP00000454168
ENST00000560611
Q9UHW9
Show all »
Show » Show » 1150 127.6 No >9
SLC12A6-011 ENSP00000452828
ENST00000559236
H0YKJ2
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135 14.8 No 0
SLC12A6-012 ENSP00000452771
ENST00000561120
H0YKE6
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152 16.9 No 0
SLC12A6-013 ENSP00000452857
ENST00000559484
H0YKL8
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61 6.6 No 0
SLC12A6-017 ENSP00000452705
ENST00000560164
B3KXX3
Show all »
Show » Show » 962 106.9 No >9
SLC12A6-018 ENSP00000454037
ENST00000560332
H0YNJ5
Show all »
Show » Show » 107 11.6 No 2
SLC12A6-020 ENSP00000454069
ENST00000561080
H0YMQ9
Show all »
Show » Show » 906 99.3 No >9
SLC12A6-201 ENSP00000390199
ENST00000451844
B3KXX3
Show all »
Show » Show » 962 106.9 No >9