DUOX2

GENE INFORMATION

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Gene name

DUOX2 (HGNC Symbol)

Synonyms

LNOX2, P138(TOX), P138-TOX, THOX2

Description

dual oxidase 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

45384848 - 45406542

Ensembl

ENSG00000140279 (version 73.37)

Entrez gene

50506

UniProt

Q9NRD8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NRD8

Antibodypedia

DUOX2 antibodies
 

PROTEIN VIEW

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DUOX2-001
 
DUOX2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DUOX2-001 ENSP00000373691
ENST00000389039
Q9NRD8
Show all »
Show » Show » 1548 175.3 Yes 9
DUOX2-201 ENSP00000475084
ENST00000603300
Show » Show » 1548 175.4 Yes 9