ETFA

GENE INFORMATION

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Gene name

ETFA (HGNC Symbol)

Synonyms

EMA, GA2, MADD

Description

electron-transfer-flavoprotein, alpha polypeptide (HGNC Symbol)

Entrez gene summary

ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q24.2

Chromosome location (bp)

76507696 - 76603813

Ensembl

ENSG00000140374 (version 73.37)

Entrez gene

2108

UniProt

P13804 (UniProt - Evidence at protein level)

neXtProt

NX_P13804

Antibodypedia

ETFA antibodies
 

PROTEIN VIEW

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 « 
 
ETFA-001
 
ETFA-002
 
ETFA-004
 
ETFA-005
 
ETFA-006
 
ETFA-007
 
ETFA-011
 
ETFA-012
 
ETFA-014
 
ETFA-015
 
ETFA-017
 
ETFA-019
 
ETFA-020
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ETFA-001 ENSP00000452762
ENST00000557943
P13804
Show all »
Show » 333 35.1 No 0
ETFA-002 ENSP00000399273
ENST00000433983
P13804
Show all »
Show » 284 30 No 0
ETFA-004 ENSP00000452942
ENST00000560044
H0YMU8
Show all »
45 5.1 No 0
ETFA-005 ENSP00000453753
ENST00000560309
H0YMU8
Show all »
45 5.1 No 0
ETFA-006 ENSP00000453098
ENST00000560726
H0YL83
Show all »
Show » 73 7.8 No 0
ETFA-007 ENSP00000453422
ENST00000560899
H0YM12
Show all »
39 4.1 No 0
ETFA-011 ENSP00000452777
ENST00000559386
H0YKF0
Show all »
Show » Show » 289 30.2 No 0
ETFA-012 ENSP00000453017
ENST00000560345
Show » 240 24.9 No 0
ETFA-014 ENSP00000452659
ENST00000559602
H0YK49
Show all »
Show » 229 24.2 No 0
ETFA-015 ENSP00000267950
ENST00000267950
J3KN60
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64 6.8 No 0
ETFA-017 ENSP00000454194
ENST00000559973
254 26.8 No 0
ETFA-019 ENSP00000453345
ENST00000560595
H0YLU7
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Show » 303 31.7 No 0
ETFA-020 ENSP00000458001
ENST00000565910
H3BV91
Show all »
46 4.9 No 0