CDH13

GENE INFORMATION

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Gene name

CDH13 (HGNC Symbol)

Synonyms

CDHH

Description

cadherin 13, H-cadherin (heart) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]

Chromosome

16 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

82660408 - 83830204

Ensembl

ENSG00000140945 (version 73.37)

Entrez gene

1012

UniProt

P55290 (UniProt - Evidence at protein level)

neXtProt

NX_P55290

Antibodypedia

CDH13 antibodies
 

PROTEIN VIEW

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 « 
 
CDH13-001
 
CDH13-003
 
CDH13-004
 
CDH13-005
 
CDH13-006
 
CDH13-007
 
CDH13-009
 
CDH13-011
 
CDH13-012
 
CDH13-013
 
CDH13-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH13-001 ENSP00000454435
ENST00000566620
P55290
Show all »
Show » Show » 713 78.3 Yes 0
CDH13-003 ENSP00000408632
ENST00000431540
P55290
Show all »
Show » 190 21.1 Yes 0
CDH13-004 ENSP00000456491
ENST00000565636
P55290
Show all »
Show » 175 19.7 Yes 0
CDH13-005 ENSP00000394557
ENST00000428848
B7Z590
Show all »
Show » Show » 674 73.8 Yes 0
CDH13-006 ENSP00000442225
ENST00000539548
F5H7W7
Show all »
52 5.9 Yes 0
CDH13-007 ENSP00000456297
ENST00000567445
H3BRL7
Show all »
67 7.6 Yes 0
CDH13-009 ENSP00000268613
ENST00000268613
P55290
Show all »
Show » Show » 760 83.4 No 0
CDH13-011 ENSP00000455781
ENST00000562601
H3BQH4
Show all »
67 7.6 Yes 0
CDH13-012 ENSP00000457914
ENST00000569144
H3BV21
Show all »
56 6.4 Yes 0
CDH13-013 ENSP00000457149
ENST00000568770
H3BTF2
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37 4 Yes 0
CDH13-201 ENSP00000388804
ENST00000446376
P55290
Show all »
Show » 175 19.7 Yes 0