IRF8

GENE INFORMATION

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Gene name

IRF8 (HGNC Symbol)

Synonyms

ICSBP, ICSBP1, IRF-8

Description

interferon regulatory factor 8 (HGNC Symbol)

Entrez gene summary

Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]

Chromosome

16 (Chromosome progress)

Cytoband

q24.1

Chromosome location (bp)

85932409 - 85956215

Ensembl

ENSG00000140968 (version 73.37)

Entrez gene

3394

UniProt

Q02556 (UniProt - Evidence at protein level)

neXtProt

NX_Q02556

Antibodypedia

IRF8 antibodies
 

PROTEIN VIEW

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IRF8-001
 
IRF8-002
 
IRF8-003
 
IRF8-004
 
IRF8-006
 
IRF8-008
 
IRF8-009
 
IRF8-010
 
IRF8-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IRF8-001 ENSP00000268638
ENST00000268638
Q02556
Show all »
Show » Show » 426 48.4 No 0
IRF8-002 ENSP00000458047
ENST00000563180
H3BVC2
Show all »
Show » Show » 126 15 No 0
IRF8-003 ENSP00000455048
ENST00000566369
Show » 152 16.8 No 0
IRF8-004 ENSP00000455816
ENST00000565552
H3BQK3
Show all »
Show » Show » 47 5.7 No 0
IRF8-006 ENSP00000456992
ENST00000564803
H3BT31
Show all »
Show » Show » 328 37.2 No 0
IRF8-008 ENSP00000455760
ENST00000569145
14 1.5 No 0
IRF8-009 ENSP00000455452
ENST00000562492
H3BPS5
Show all »
Show » Show » 222 24.9 No 0
IRF8-010 ENSP00000456395
ENST00000569607
H3BRT4
Show all »
Show » Show » 220 24.7 No 0
IRF8-011 ENSP00000455784
ENST00000564617
H3BQH6
Show all »
Show » Show » 159 18.5 No 0