SKAP1

GENE INFORMATION

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Gene name

SKAP1 (HGNC Symbol)

Synonyms

SCAP1, SKAP55

Description

src kinase associated phosphoprotein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q21.32

Chromosome location (bp)

46210802 - 46507637

Ensembl

ENSG00000141293 (version 73.37)

Entrez gene

8631

UniProt

Q86WV1 (UniProt - Evidence at protein level)

neXtProt

NX_Q86WV1

Antibodypedia

SKAP1 antibodies
 

PROTEIN VIEW

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SKAP1-001
 
SKAP1-002
 
SKAP1-003
 
SKAP1-004
 
SKAP1-005
 
SKAP1-006
 
SKAP1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SKAP1-001 ENSP00000338171
ENST00000336915
Q86WV1
Show all »
Show » Show » 359 41.4 No 0
SKAP1-002 ENSP00000464311
ENST00000584924
Q86WV1
Show all »
Show » Show » 359 41.4 No 0
SKAP1-003 ENSP00000463284
ENST00000584709
J3QKX8
Show all »
103 11.8 No 0
SKAP1-004 ENSP00000462437
ENST00000581419
J3KSD4
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38 4.1 No 0
SKAP1-005 ENSP00000464198
ENST00000579336
J3QRG3
Show all »
Show » 99 11.3 No 0
SKAP1-006 ENSP00000462360
ENST00000581400
Show » 92 10.4 No 0
SKAP1-008 ENSP00000464509
ENST00000583844
J3QS38
Show all »
Show » Show » 32 3.8 No 0