ARSG

GENERAL INFORMATION

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Gene name

ARSG

Gene description

Arylsulfatase G

Protein class

Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Highly specific cytoplasmic expression in exocrine pancreas. RNAS4

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA023245 , HPA023285
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

ARSG (HGNC Symbol)

Synonyms

KIAA1001

Description

Arylsulfatase G (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Chromosome

17

Cytoband

q24.2

Chromosome location (bp)

68259182 - 68422731

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141337 (version 78.38)

Entrez gene

22901

UniProt

Q96EG1 (UniProt - Evidence at protein level)

neXtProt

NX_Q96EG1

Antibodypedia

ARSG antibodies


PROTEIN BROWSER

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ENST00000448504
 
ENST00000452479
 
ENST00000581639
 
ENST00000621439
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARSG-002 ENSP00000407193
ENST00000448504
Q96EG1
Show all »
Show » Show » 525 57.1 Yes 0
ARSG-003 ENSP00000413953
ENST00000452479
J9JIG6
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Show » Show » 361 39.2 No 0
ARSG-004 ENSP00000462306
ENST00000581639
J3KS49
Show all »
Show » 29 3.2 Yes 0
ARSG-201 ENSP00000480910
ENST00000621439
Q96EG1
Show all »
Show » Show » 525 57.1 Yes 0