ABCA8

GENE INFORMATION

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Gene name

ABCA8 (HGNC Symbol)

Synonyms

KIAA0822

Description

ATP-binding cassette, sub-family A (ABC1), member 8 (HGNC Symbol)

Entrez gene summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Chromosome

17

Cytoband

q24.2

Chromosome location (bp)

68867292 - 68955392

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141338 (version 78.38)

Entrez gene

10351

UniProt

O94911 (UniProt - Evidence at protein level)

neXtProt

NX_O94911

Antibodypedia

ABCA8 antibodies
 

PROTEIN VIEW

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ABCA8-001
 
ABCA8-003
 
ABCA8-009
 
ABCA8-201
 
ABCA8-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCA8-001 ENSP00000269080
ENST00000269080
O94911
Show all »
Show » Show » 1581 179.2 No >9
ABCA8-003 ENSP00000467271
ENST00000586539
O94911
Show all »
Show » Show » 1621 183.7 No >9
ABCA8-009 ENSP00000466126
ENST00000585531
K7ELK9
Show all »
Show » 115 13.4 No 1
ABCA8-201 ENSP00000402814
ENST00000430352
K7ELK9
Show all »
Show » Show » 1616 183.1 No >9
ABCA8-202 ENSP00000481467
ENST00000615593
Q49AI9
Show all »
Show » 156 17.9 No 1