G6PC3

GENE INFORMATION

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Gene name

G6PC3 (HGNC Symbol)

Synonyms

UGRP

Description

glucose 6 phosphatase, catalytic, 3 (HGNC Symbol)

Entrez gene summary

This gene encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein.[provided by RefSeq, Sep 2009]

Chromosome

17 (Chromosome progress)

Cytoband

q21.31

Chromosome location (bp)

42148103 - 42153709

Ensembl

ENSG00000141349 (version 73.37)

Entrez gene

92579

UniProt

Q9BUM1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BUM1

Antibodypedia

G6PC3 antibodies
 

PROTEIN VIEW

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G6PC3-001
 
G6PC3-002
 
G6PC3-003
 
G6PC3-004
 
G6PC3-006
 
G6PC3-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

G6PC3-001 ENSP00000269097
ENST00000269097
Q9BUM1
Show all »
Show » Show » 346 38.7 No 9
G6PC3-002 ENSP00000467624
ENST00000588558
K7EQ13
Show all »
Show » Show » 72 8.3 No 1
G6PC3-003 ENSP00000466983
ENST00000585361
K7ENK1
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Show » Show » 73 8.5 No 2
G6PC3-004 ENSP00000465111
ENST00000590253
69 7.2 No 0
G6PC3-006 ENSP00000466821
ENST00000593115
K7ENK1
Show all »
Show » Show » 73 8.5 No 2
G6PC3-007 ENSP00000468677
ENST00000591696
K7ESE6
Show all »
Show » Show » 243 27.6 No 5