GNAL

GENERAL INFORMATION

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Gene name

GNAL

Gene description

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Most normal cells showed moderate to strong cytoplasmic and nuclear staining.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
CAB015464
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

GNAL

Synonyms

Description

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (HGNC Symbol)

Entrez gene summary

This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Chromosome

18

Cytoband

p11.21

Chromosome location (bp)

11688956 - 11885685

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141404 (version 78.38)

Entrez gene

2774

UniProt

P38405 (UniProt - Evidence at protein level)

neXtProt

NX_P38405

Antibodypedia

GNAL antibodies


PROTEIN BROWSER

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ENST00000269162
 
ENST00000334049
 
ENST00000423027
 
ENST00000535121
 
ENST00000585642
 
ENST00000586926
 
ENST00000590228
 
ENST00000602628
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GNAL-001 ENSP00000334051
ENST00000334049
P38405
Show all »
Show » Show » 458 52.5 No 0
GNAL-002 ENSP00000408489
ENST00000423027
P38405
Show all »
Show » Show » 381 44.3 No 0
GNAL-004 ENSP00000269162
ENST00000269162
P38405
Show all »
Show » Show » 381 44.3 No 0
GNAL-005 ENSP00000439023
ENST00000535121
P38405
Show all »
Show » Show » 381 44.3 No 0
GNAL-006 ENSP00000473600
ENST00000602628
P38405
Show all »
Show » Show » 174 20.5 No 0
GNAL-008 ENSP00000467345
ENST00000585642
K7EPE2
Show all »
Show » Show » 179 20.9 No 0
GNAL-009 ENSP00000467709
ENST00000590228
K7EQ80
Show all »
Show » Show » 145 17 No 0
GNAL-011 ENSP00000466709
ENST00000586926
Show » 54 6 No 0