SLC39A6

GENERAL INFORMATION

? »

Gene name

SLC39A6

Gene description

Solute carrier family 39 (zinc transporter), member 6

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression. Additional nuclear expression in several tissues.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA042377
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

SLC39A6 (HGNC Symbol)

Synonyms

LIV-1

Description

Solute carrier family 39 (zinc transporter), member 6 (HGNC Symbol)

Entrez gene summary

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

Chromosome

18

Cytoband

q12.2

Chromosome location (bp)

36108532 - 36129385

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141424 (version 78.38)

Entrez gene

25800

UniProt

Q13433 (UniProt - Evidence at protein level)

neXtProt

NX_Q13433

Antibodypedia

SLC39A6 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000269187
 
ENST00000440549
 
ENST00000586829
 
ENST00000590986
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC39A6-001 ENSP00000401139
ENST00000440549
Q13433
Show all »
Show » Show » 433 48.6 No 5
SLC39A6-002 ENSP00000269187
ENST00000269187
Q13433
Show all »
Show » Show » 755 85 Yes 6
SLC39A6-004 ENSP00000465915
ENST00000590986
Q13433
Show all »
Show » Show » 755 85 Yes 6
SLC39A6-005 ENSP00000467724
ENST00000586829
K7EQ91
Show all »
Show » Show » 273 30.9 No 2