GALNT1

GENE INFORMATION

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Gene name

GALNT1 (HGNC Symbol)

Synonyms

GalNAc-T1

Description

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. [provided by RefSeq, Jul 2008]

Chromosome

18 (Chromosome progress)

Cytoband

q12.2

Chromosome location (bp)

33161081 - 33291798

Ensembl

ENSG00000141429 (version 73.37)

Entrez gene

2589

UniProt

Q10472 (UniProt - Evidence at protein level)

neXtProt

NX_Q10472

Antibodypedia

GALNT1 antibodies
 

PROTEIN VIEW

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GALNT1-001
 
GALNT1-002
 
GALNT1-003
 
GALNT1-004
 
GALNT1-006
 
GALNT1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GALNT1-001 ENSP00000269195
ENST00000269195
Q10472
Show all »
Show » Show » 559 64.2 No 1
GALNT1-002 ENSP00000466411
ENST00000591081
Q10472
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Show » Show » 105 12 No 0
GALNT1-003 ENSP00000465452
ENST00000590654
K7EK46
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Show » 50 5.8 No 0
GALNT1-004 ENSP00000465341
ENST00000589189
K7EJV8
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Show » Show » 387 44.4 No 1
GALNT1-006 ENSP00000465699
ENST00000591924
Q10472
Show all »
Show » Show » 105 12 No 0
GALNT1-201 ENSP00000440910
ENST00000537549
F5GY99
Show all »
Show » 499 57.4 No 0