MINK1

GENE INFORMATION

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Gene name

MINK1 (HGNC Symbol)

Synonyms

B55, MAP4K6, MINK, YSK2, ZC3

Description

misshapen-like kinase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

4736683 - 4801356

Ensembl

ENSG00000141503 (version 73.37)

Entrez gene

50488

UniProt

Q8N4C8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N4C8

Antibodypedia

MINK1 antibodies
 

PROTEIN VIEW

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MINK1-001
 
MINK1-002
 
MINK1-003
 
MINK1-005
 
MINK1-006
 
MINK1-009
 
MINK1-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MINK1-001 ENSP00000347427
ENST00000355280
Q8N4C8
Show all »
Show » Show » 1332 149.8 No 0
MINK1-002 ENSP00000269296
ENST00000347992
Q8N4C8
Show all »
Show » Show » 1303 146.7 No 0
MINK1-003 ENSP00000406487
ENST00000453408
Q8N4C8
Show all »
Show » Show » 1312 147.7 No 0
MINK1-005 ENSP00000461500
ENST00000574453
I3L4T2
Show all »
111 12.9 No 0
MINK1-006 ENSP00000459699
ENST00000571207
Show » 381 44.9 No 0
MINK1-009 ENSP00000459269
ENST00000577021
Show » 53 5.5 No 0
MINK1-014 ENSP00000459102
ENST00000576037
I3L1U1
Show all »
Show » 161 18.1 No 0