CARD14

GENE INFORMATION

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Gene name

CARD14 (HGNC Symbol)

Synonyms

BIMP2, CARMA2

Description

caspase recruitment domain family, member 14 (HGNC Symbol)

Entrez gene summary

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]

Chromosome

17 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

78143791 - 78183130

Ensembl

ENSG00000141527 (version 73.37)

Entrez gene

79092

UniProt

Q9BXL6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXL6

Antibodypedia

CARD14 antibodies
 

PROTEIN VIEW

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CARD14-001
 
CARD14-003
 
CARD14-004
 
CARD14-009
 
CARD14-011
 
CARD14-016
 
CARD14-201
 
CARD14-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CARD14-001 ENSP00000458715
ENST00000573882
Q9BXL6
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Show » 1004 113.3 No 0
CARD14-003 ENSP00000460883
ENST00000575500
I3L414
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Show » 493 54 No 0
CARD14-004 ENSP00000460405
ENST00000571450
E7ETJ2
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Show » 475 53.3 No 0
CARD14-009 ENSP00000461447
ENST00000576785
I3L4Q8
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44 5.3 No 0
CARD14-011 ENSP00000459244
ENST00000575465
I3L4Q8
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Show » 70 8.2 No 0
CARD14-016 ENSP00000461806
ENST00000570421
Q9BXL6
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Show » 740 83.7 No 0
CARD14-201 ENSP00000344549
ENST00000344227
Q9BXL6
Show all »
Show » 1004 113.3 No 0
CARD14-202 ENSP00000376229
ENST00000392434
E7ETJ2
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Show » 441 49.4 No 0