GRB7

GENE INFORMATION

? »

Gene name

GRB7

Synonyms

Description

Growth factor receptor-bound protein 7 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Chromosome

17

Cytoband

q12

Chromosome location (bp)

37894180 - 37903544

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141738 (version 75.37)

Entrez gene

2886

UniProt

Q14451 (UniProt - Evidence at protein level)

neXtProt

NX_Q14451

Antibodypedia

GRB7 antibodies
 

PROTEIN VIEW

? »
 
 
 
GRB7-001
 
GRB7-002
 
GRB7-003
 
GRB7-006
 
GRB7-009
 
GRB7-011
 
GRB7-012
 
GRB7-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRB7-001 ENSP00000310771
ENST00000309156
Q14451
Show all »
Show » Show » 532 59.7 No 0
GRB7-002 ENSP00000377761
ENST00000394211
Q14451
Show all »
Show » Show » 532 59.7 No 0
GRB7-003 ENSP00000377754
ENST00000394204
Q14451
Show all »
Show » Show » 447 49.4 No 0
GRB7-006 ENSP00000403459
ENST00000445327
Q14451
Show all »
Show » Show » 555 62.1 No 0
GRB7-009 ENSP00000377759
ENST00000394209
Q14451
Show all »
Show » Show » 532 59.7 No 0
GRB7-011 ENSP00000463416
ENST00000577695
J3QL76
Show all »
Show » 118 12.6 No 0
GRB7-012 ENSP00000463126
ENST00000583813
J3QKK7
Show all »
Show » 52 5.4 No 0
GRB7-201 ENSP00000311752
ENST00000309185
Q14451
Show all »
Show » Show » 447 49.4 No 0