PNMT

GENE INFORMATION

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Gene name

PNMT (HGNC Symbol)

Synonyms

PENT

Description

phenylethanolamine N-methyltransferase (HGNC Symbol)

Entrez gene summary

The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]

Chromosome

17 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

37824234 - 37826728

Ensembl

ENSG00000141744 (version 73.37)

Entrez gene

5409

UniProt

P11086 (UniProt - Evidence at protein level)

neXtProt

NX_P11086

Antibodypedia

PNMT antibodies
 

PROTEIN VIEW

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PNMT-001
 
PNMT-002
 
PNMT-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PNMT-001 ENSP00000269582
ENST00000269582
P11086
Show all »
Show » Show » 282 30.9 No 0
PNMT-002 ENSP00000377791
ENST00000394246
A8MT87
Show all »
Show » 184 20.6 No 0
PNMT-003 ENSP00000464234
ENST00000581428
J3QRI3
Show all »
Show » 137 14.9 No 0