IGFBP4

GENE INFORMATION

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Gene name

IGFBP4 (HGNC Symbol)

Synonyms

BP-4, HT29-IGFBP, IBP4, IGFBP-4

Description

insulin-like growth factor binding protein 4 (HGNC Symbol)

Entrez gene summary

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q21.2

Chromosome location (bp)

38599702 - 38613983

Ensembl

ENSG00000141753 (version 73.37)

Entrez gene

3487

UniProt

P22692 (UniProt - Evidence at protein level)

neXtProt

NX_P22692

Antibodypedia

IGFBP4 antibodies
 

PROTEIN VIEW

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IGFBP4-001
 
IGFBP4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IGFBP4-001 ENSP00000269593
ENST00000269593
P22692
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Show » 258 27.9 Yes 0
IGFBP4-201 ENSP00000437734
ENST00000542955
B4E351
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Show » 158 17.6 No 0