BRD4

GENE INFORMATION

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Gene name

BRD4 (HGNC Symbol)

Synonyms

CAP, HUNK1, HUNKI, MCAP

Description

bromodomain containing 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.12

Chromosome location (bp)

15347647 - 15443356

Ensembl

ENSG00000141867 (version 73.37)

Entrez gene

23476

UniProt

O60885 (UniProt - Evidence at protein level)

neXtProt

NX_O60885

Antibodypedia

BRD4 antibodies
 

PROTEIN VIEW

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BRD4-001
 
BRD4-002
 
BRD4-003
 
BRD4-004
 
BRD4-005
 
BRD4-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BRD4-001 ENSP00000263377
ENST00000263377
O60885
Show all »
Show » Show » 1362 152.2 No 0
BRD4-002 ENSP00000360901
ENST00000371835
O60885
Show all »
Show » Show » 722 80.5 No 0
BRD4-003 ENSP00000353112
ENST00000360016
Q4G0X8
Show all »
Show » Show » 794 88.3 No 0
BRD4-004 ENSP00000470481
ENST00000594841
M0QZD9
Show all »
Show » Show » 572 63.8 No 0
BRD4-005 ENSP00000470108
ENST00000597315
M0QYW0
Show all »
Show » Show » 146 16.9 No 0
BRD4-008 ENSP00000471240
ENST00000601941
M0R0H4
Show all »
Show » Show » 105 11.7 No 0