ADAMTS10

GENE INFORMATION

? »

Gene name

ADAMTS10 (HGNC Symbol)

Synonyms

ADAM-TS10

Description

ADAM metallopeptidase with thrombospondin type 1 motif, 10 (HGNC Symbol)

Entrez gene summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

8645126 - 8675620

Ensembl

ENSG00000142303 (version 73.37)

Entrez gene

81794

UniProt

Q9H324 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H324

Antibodypedia

ADAMTS10 antibodies
 

PROTEIN VIEW

? »
 
 
 
ADAMTS10-001
 
ADAMTS10-002
 
ADAMTS10-003
 
ADAMTS10-005
 
ADAMTS10-011
 
ADAMTS10-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAMTS10-001 ENSP00000471851
ENST00000597188
Q9H324
Show all »
Show » Show » 1103 120.9 Yes 0
ADAMTS10-002 ENSP00000469559
ENST00000596851
M0QY36
Show all »
Show » 289 32.4 Yes 0
ADAMTS10-003 ENSP00000470501
ENST00000595838
M0QZE4
Show all »
Show » 590 62.5 No 0
ADAMTS10-005 ENSP00000469901
ENST00000593913
M0QY36
Show all »
Show » 289 32.4 Yes 0
ADAMTS10-011 ENSP00000469516
ENST00000593826
M0QY12
Show all »
126 12.3 No 0
ADAMTS10-201 ENSP00000270328
ENST00000270328
Q9H324
Show all »
Show » Show » 1103 120.9 Yes 0