EPHA2

GENE INFORMATION

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Gene name

EPHA2 (HGNC Symbol)

Synonyms

ECK

Description

EPH receptor A2 (HGNC Symbol)

Entrez gene summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]

Chromosome

1 (Chromosome progress)

Cytoband

p36.13

Chromosome location (bp)

16450832 - 16482582

Ensembl

ENSG00000142627 (version 73.37)

Entrez gene

1969

UniProt

P29317 (UniProt - Evidence at protein level)

neXtProt

NX_P29317

Antibodypedia

EPHA2 antibodies
 

PROTEIN VIEW

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EPHA2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHA2-001 ENSP00000351209
ENST00000358432
P29317
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