MAP3K6

GENE INFORMATION

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Gene name

MAP3K6 (HGNC Symbol)

Synonyms

ASK2, MAPKKK6, MEKK6

Description

mitogen-activated protein kinase kinase kinase 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the serine/threonine protein kinase family. The encoded kinase was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase. This kinase was found to weakly activate MAPK7, but not MAPK1/ERK or MAPK14. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p36.11

Chromosome location (bp)

27681675 - 27693383

Ensembl

ENSG00000142733 (version 73.37)

Entrez gene

9064

UniProt

O95382 (UniProt - Evidence at protein level)

neXtProt

NX_O95382

Antibodypedia

MAP3K6 antibodies
 

PROTEIN VIEW

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MAP3K6-001
 
MAP3K6-002
 
MAP3K6-006
 
MAP3K6-007
 
MAP3K6-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAP3K6-001 ENSP00000419591
ENST00000493901
O95382
Show all »
Show » Show » 1288 142.6 No 0
MAP3K6-002 ENSP00000418731
ENST00000472410
Q32MQ5
Show all »
Show » Show » 798 88.7 No 0
MAP3K6-006 ENSP00000418932
ENST00000486046
82 9.1 No 0
MAP3K6-007 ENSP00000350195
ENST00000357582
O95382
Show all »
Show » Show » 1288 142.6 No 0
MAP3K6-008 ENSP00000363152
ENST00000374040
O95382
Show all »
Show » Show » 1280 141.6 No 0