RPS8

GENERAL INFORMATION

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Gene name

RPS8

Gene description

Ribosomal protein S8

Protein class

Plasma proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Strong cytoplasmic and nuclear positivity was observed in Purkinje cells. Stomach, duodenum, exocrine pancreas, neuronal cells and subsets of bone marrow poietic cells displayed moderately cytoplasmic stained. Remaining normal cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA029266
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

RPS8 (HGNC Symbol)

Synonyms

S8

Description

Ribosomal protein S8 (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p34.1

Chromosome location (bp)

44775251 - 44778779

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142937 (version 78.38)

Entrez gene

6202

UniProt

P62241 (UniProt - Evidence at protein level)

neXtProt

NX_P62241

Antibodypedia

RPS8 antibodies


PROTEIN BROWSER

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ENST00000372209
 
ENST00000396651
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPS8-001 ENSP00000379888
ENST00000396651
P62241
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Show » Show » 208 24.2 No 0
RPS8-003 ENSP00000361283
ENST00000372209
Q5JR95
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Show » Show » 188 21.9 No 0