BEST4

GENE INFORMATION

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Gene name

BEST4 (HGNC Symbol)

Synonyms

VMD2L2

Description

bestrophin 4 (HGNC Symbol)

Entrez gene summary

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p34.1

Chromosome location (bp)

45249257 - 45253377

Ensembl

ENSG00000142959 (version 73.37)

Entrez gene

266675

UniProt

Q8NFU0 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NFU0

Antibodypedia

BEST4 antibodies
 

PROTEIN VIEW

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BEST4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BEST4-001 ENSP00000361281
ENST00000372207
Q8NFU0
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