KCNA10

GENE INFORMATION

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Gene name

KCNA10 (HGNC Symbol)

Synonyms

Kv1.8

Description

potassium voltage-gated channel, shaker-related subfamily, member 10 (HGNC Symbol)

Entrez gene summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

111059839 - 111061797

Ensembl

ENSG00000143105 (version 73.37)

Entrez gene

3744

UniProt

Q16322 (UniProt - Evidence at protein level)

neXtProt

NX_Q16322

Antibodypedia

KCNA10 antibodies
 

PROTEIN VIEW

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KCNA10-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNA10-001 ENSP00000358786
ENST00000369771
Q16322
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