PSMA5

GENE INFORMATION

? »

Gene name

PSMA5 (HGNC Symbol)

Synonyms

ZETA

Description

proteasome (prosome, macropain) subunit, alpha type, 5 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Chromosome

1 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

109941653 - 109969062

Ensembl

ENSG00000143106 (version 73.37)

Entrez gene

5686

UniProt

P28066 (UniProt - Evidence at protein level)

neXtProt

NX_P28066

Antibodypedia

PSMA5 antibodies
 

PROTEIN VIEW

? »
 
 
 
PSMA5-001
 
PSMA5-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMA5-001 ENSP00000271308
ENST00000271308
P28066
Show all »
Show » Show » 241 26.4 No 0
PSMA5-201 ENSP00000440618
ENST00000538610
P28066
Show all »
Show » Show » 183 20 No 0