CELSR2

GENE INFORMATION

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Gene name

CELSR2 (HGNC Symbol)

Synonyms

CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3

Description

cadherin, EGF LAG seven-pass G-type receptor 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

109792641 - 109818372

Ensembl

ENSG00000143126 (version 73.37)

Entrez gene

1952

UniProt

Q9HCU4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HCU4

Antibodypedia

CELSR2 antibodies
 

PROTEIN VIEW

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CELSR2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CELSR2-001 ENSP00000271332
ENST00000271332
Q9HCU4
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