ADCY10

GENE INFORMATION

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Gene name

ADCY10 (HGNC Symbol)

Synonyms

HCA2, RP1-313L4.2, SAC, SACI, Sacy

Description

Adenylate cyclase 10 (soluble) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Genetic variations in this gene are associated with absorptive hypercalciuria type 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

Chromosome

1

Cytoband

q24.2

Chromosome location (bp)

167778625 - 167883453

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143199 (version 75.37)

Entrez gene

55811

UniProt

Q96PN6 (UniProt - Evidence at protein level)

neXtProt

NX_Q96PN6

Antibodypedia

ADCY10 antibodies
 

PROTEIN VIEW

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ADCY10-001
 
ADCY10-002
 
ADCY10-003
 
ADCY10-004
 
ADCY10-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADCY10-001 ENSP00000356825
ENST00000367851
Q96PN6
Show all »
Show » Show » 1610 187.1 No 4
ADCY10-002 ENSP00000356822
ENST00000367848
Q96PN6
Show all »
Show » Show » 1518 176.6 No 4
ADCY10-003 ENSP00000476402
ENST00000485964
Show » 250 29.1 No 0
ADCY10-004 ENSP00000475192
ENST00000476818
U3KPS9
Show all »
Show » 73 8.7 No 0
ADCY10-005 ENSP00000441992
ENST00000545172
Q96PN6
Show all »
Show » Show » 1457 169.7 No 5